Eastern Panama Holidays from AU$921

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Your Eastern Panama Holiday

Leave all the planning to us with an Eastern Panama holiday package. With everything organised before you jet off, all you need to do is sit back, chill out and experience this destination's many wonders. Where to start your journey? In the most popular cities, of course. Isla Tigre and Palenque are two great places to kick off your itinerary during your trip to Eastern Panama. When it's time to stop daydreaming and start doing, Expedia will help turn your Eastern Panama holiday into reality.

The Latest Eastern Panama Holiday Deals

Price found within the past 48 hours. Click for updated prices.
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Price was AU$1,133, price is now AU$921 per person
AU$921
per person
28 Aug - 30 Aug
found 1 day ago
Return flight included
Kingston (KIN) to Panama City (PTY)
8.4/10 Very good! (1,815 reviews)
Todo fue perfecto

Reviewed on 9 July 2026

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Price was AU$1,547, price is now AU$1,132 per person
AU$1,132
per person
28 Aug - 30 Aug
found 1 day ago
Return flight included
Kingston (KIN) to Panama City (PTY)
9.2/10 Wonderful! (1,001 reviews)
All good

Reviewed on 8 July 2026

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Price was AU$1,268, price is now AU$945 per person
AU$945
per person
28 Aug - 30 Aug
found 1 day ago
Return flight included
Kingston (KIN) to Panama City (PTY)
8.4/10 Very good! (1,574 reviews)
The breakfast was extraordinary, tasty flavorful. The service at bazaar by the staff was accommodating and helpful. The view from my room was spectacular. I found the staff to be well mannered and approachable. I will visit again.

Reviewed on 10 July 2026

Hyatt Regency Panama City

Hyatt Regency Panama City

5 out of 5
Bella Vista
Price was AU$1,154, price is now AU$1,014 per person
AU$1,014
per person
28 Aug - 30 Aug
found 1 day ago
Return flight included
Kingston (KIN) to Panama City (PTY)
9.6/10 Exceptional! (355 reviews)
Nice

Reviewed on 2 July 2026

Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo

4.5 out of 5
Casco Viejo
Price was AU$1,643, price is now AU$1,474 per person
AU$1,474
per person
28 Aug - 30 Aug
found 1 day ago
Return flight included
Kingston (KIN) to Panama City (PTY)
9.8/10 Exceptional! (314 reviews)
Great place! I highly recommend.

Reviewed on 10 July 2026

Eastern Panama Holiday

Eastern Panama Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Tocumen Intl. Airport (PTY)
Top Sights
Portobelo National Park, Isla Mamey and Cayos Holandeses

Our pick of the best Eastern Panama Hotel Deals

Ordovician Beach Resort

Ordovician Beach Resort

4.5 out of 5
Isla Grande Isla Grande Colon
The price is AU$706 per night from 13 July to 14 July
AU$706
13 July - 14 July
includes taxes & fees
10/10 Exceptional! (12 reviews)
"This resort is one of those special places you find that redefines a vacation. It is about a 15 minute boat ride from the dock, occupying the back side of Isla Grande and looking out to the Caribbean Sea. We were there during low season in July, and were fortunate enough to be one of just a few visitors ..."

Reviewed on 8 July 2026

Ordovician Beach Resort
san blas luxury tour

san blas luxury tour

2 out of 5
guna yala Nusatupo Guna Yala
The price is AU$229 per night from 13 July to 14 July
AU$229
13 July - 14 July
includes taxes & fees
san blas luxury tour
HOTEL ISLA GRANDE

HOTEL ISLA GRANDE

3 out of 5
Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province
The price is AU$157 per night from 12 July to 13 July
AU$157
12 July - 13 July
includes taxes & fees
HOTEL ISLA GRANDE
See all 192 properties in Eastern Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
All Inclusive Holidays
Cheap Holidays
Cheap Holidays
Cheap Holidays
beach holidays
Beach Holidays
Beach Holidays

Stay near popular Eastern Panama attractions

Isla Diablo

Commune with nature and explore the great outdoors at Isla Diablo during your travels in San Blas Islands. Take in the festivals while you're in the area.
See properties

Frequently asked questions

How much does an Eastern Panama holiday package cost?
The most affordable Eastern Panama holiday package is AU$921, so your dream getaway can become a reality — without breaking the bank. Bundle flights, hotels and car rentals to tailor make a package that matches your travelling style.
How do I get a cheap travel package to Eastern Panama?
Lock in flights that suit your schedule, add a hotel to your booking and watch the savings pile up with an Eastern Panama holiday package. It's as simple as that! From flights and hotels to rental cars and activities, Expedia is where your cheap getaway begins. And with over 550 air carriers and 1 000 000 hotels around the world to choose from, you won't be short of choice.
What are the top hotels in Eastern Panama?
For hotels in San Blas Islands with friendly service and cosy beds, look up Private Over The Water Cabin On San Blas Island and San Blas Private Over - The - Water Cabin. If you plan to explore Narganá as well, you can look forward to a great night's sleep at Paradise Over The Water Cabins In San Blas or San Blas Private Over - The - Water Cabin.
How far in advance should I book my Eastern Panama holiday?
Smart travellers often reserve their seats as early as possible. You can generally look up international fares on Expedia up to 12 months before your intended flight. If you're booking last minute, don't despair. Low prices sometimes occur just weeks prior to departure.
What does an Expedia Eastern Panama travel package include?
Flights, rental cars and hotels, or any combination of the three — it's your choice. Whether you're visiting Eastern Panama with the kids or travelling by yourself, there's a package to fit every style and budget. Once you've made your booking, why not add on a couple of tours or activities?
What should I know before booking an Eastern Panama travel package?
Booking all the parts of your getaway together is an excellent way to save. Combine your car rentals, flights and hotels into a neat little package. But it's not just hotels. Expedia features all types of properties, including holiday homes like mountain cabins and city apartments. Your choices are almost endless!
Can I choose my airline with an Eastern Panama Expedia holiday package?
Yes — that's the beauty of an Expedia holiday package. You're in charge! We have access to more than 550 airline partners across the globe, so you have loads of choice when planning your Eastern Panama getaway.
If I'm not able to travel, can I cancel my Eastern Panama holiday package?
You can. We realise life doesn't always go to plan, so we're happy to help if you have to make changes to your Eastern Panama holiday package. You may be able to cancel or change your itinerary for free if you've booked within 24 hours. Your hotel, airline or car rental company may charge you a fee if your booking was made more than 24 hours ago. Look up our Customer Service Portal for more information. Also, check your itinerary for the finer details on change fees.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.